Paul S. van Bemmelen, MD; David B. Gitlitz, MD; Rishad M. Faruqi, MD; Joan Weiss-Olmanni, RVT; Valerie A. Brunetti, DPM, FACFAS; Fabio Giron, MD; John J. Ricotta, MD
Departments of Vascular Surgery and Podiatry, VA Medical Center, Northport, NY; and the Division of Vascular Surgery, State University of New York at Stony Brook.
Arch Surg. 2001136:1280-1285
Hypothesis: Intermittent compression therapy for patients with inoperable chronic critical ischemia with rest pain or tissue loss may have beneficial clinical and hemodynamic effects.
Study Design: Case series of 14 consecutive ischemic legs that underwent application of a 3-month treatment protocol during a 2 1/2 year study.
Setting: Veterans Administration Hospital.
Patients: Thirteen patients with 14 critically ischemic legs (rest pain, n=14; tissue loss, n=13) who were not candidates for surgical reconstruction were treated with rapid high-pressure intermittent compression. The patients had a mean age of 76.2 years, 8 were diabetic, and they represented 10% of referrals for chronic critical ischemia. They were not amenable to revascularization owing to lack of outflow arteries (n=7), lack of autogenous vein (n=5), or poor general medical conditiona (n=3).
Intervention: All patients were instructed to use the arterial assist device for 4 hours a day at home for a 3-month period.
Main Outcome Measures: Limb salvage and calibrated pulse volume amplitude.
Results: After 3 months, 9 legs had a significant increase in pulse-volume amplitude (P<.05). These legs were salvaged, whereas the 4 amputated legs demonstrated no hemodynamic improvement. We noted a direct correlation between patient compliance and clinical outcome. Patients in whom limb salvage was achieved used their compression device for longer periods of time (mean time, 2.38 hours a day) compared with those who underwent amputation (mean time, 1,14 hours a day) (P<.05). These mean hours of use were derived from an hour counter built into the compression units.
Conclusions: Intermittent high-pressure compression may allow limb salvage in patients with limb-threatening ischemia who are not candidates for revascularization. Further studies are warranted to assess intermittent compression as an alternative to amputation in an increasingly older patient population.
